Blasto is very anti-establishment and withdrawn from society, although he does not hate it. He even had aspirations of meeting a woman who appreciated his "art" (his creations), settling down and having children. He is quite laid-back; this may be due to smoking marijuana regularly.
He is wary and skeptical of others, expecting traps at any moment from Accord, confident in his abilities and appreciates the work of other tinkers, such as Dragon. However, he had grown used to substandard equipment, and was excited at the prospect of a real lab.
He has no problem with dutifully executing those of his creations which are doomed to fail. At one point, he tried composing a pseudo-endbringer using tissue samples from both Myrddin and the Simurgh, which is something that Bonesaw later admits that "she's not even crazy enough to do".
Blasto was of presumably average height, being taller than accord, with brown hair. He generally wore a fungus-based biological masks. Early in his career these would be more like a typical mask completely obscuring his face. Later he was able to refine it so it mimicked the texture and appearance of a normal face.
Blasto is a "wet" tinker, often working with plants, fungi and animals to create weaponized hybrids, which he uses to wreak havoc upon his enemies, using pheromones to control them.
He can create life-forms using raw materials, such as a lab assistant, a pseudo-endbringer and other, non-specified hybrids. He deliberately makes his creations sterile, as he was warned that self-replicating beings would constitute an S-Class threat which would mean a kill order for him.
Blasto was one of the only kids in his town to go to medical school. It created a rift between him and his family and friends. He was too 'uppity' to belong anywhere at home and too much of a welfare case to get acceptance from school peers or professors. Caught between the two, he saw both realities crumble. His father was sent to jail, his brother targeted, his sister at risk with no one to protect her, while the doctor he was interning for ignored him and effectively sabotaged him. He triggered.
After Blasto triggered, he threw himself into his work..
Blasto and his girlfriend, Rotten Apple, started growing their own 'green'-themed faction, Blastgerm, for the sake of increasing their influence during the power vacuum.
They quickly made an enemy out of Accord by rudely declining his plans and being generally distasteful.
Blasto's HQ was the second target of Damsel of Distress. After installing some much needed ventilation in the building, she agreed to keep their messy secret in exchange for Blastgerms assets.
Made a green giant, that scared at least a half of the city, without doing much of anything. Blasto was somehow able to weave into giant some power expression, so it would have enough durability to move. Blasto explained that it served mostly as a symbol of his claim on South Boston. It was destroyed by Damsel on her way out of Boston.
Blasto was the crime lord of East Allston since April 2009. He had committed second-degree murder and was noted for mass property damage during his crimes. He was enemies with Accord,Spree and Chain Man.
After Blasto's lab was destroyed, ostensibly by remnants of the Empire Eighty-Eight, Accord proposed a peace. In exchange for a cessation of hostilities and part of Blasto's territory, Accord provided an equipped laboratory with various samples of highly classified material. 
However, disaster struck when Bonesaw and Damsel of Distress showed up, trying to weaponize tinker's works, in order to move the apocalypse along. Defiant then tried to kill Bonesaw, and did kill Damsel. Bonesaw then took control of Blasto's body, gathered all the various DNA samples from past members of the Slaughterhouse Nine, and left, still in control of his body.
He finally died under torture in the Slaughterhouse 9's private world.
↑There were three capes with a plant theme. A guy with frizzy brown hair sticking out over the top and sides of a mask that looked like it was made of the softest rubber, all in oval-shaped nodules. More mushroom-like nodules stood out diagonally from his shoulders. A man sat on a rock beside him, foot propped up on a creature that looked like it was made of driftwood, a snake with two forelimbs and no rear legs. A woman stood in the shadows behind them. She had no name for them. - Excerpt from Eclipse x.2
“Yes,” Rey replied. He folded one corner of his face back. “It’s a fungus. Same texture as human flesh.”- Excerpt from Interlude 19.x
↑Blasto was one of the only kids in his town to go to med school. It created a rift between him and his family and his friends. He was too 'uppity' to belong anywhere at home and too much of a welfare case to get the acceptance of school peers or professor. Caught between the two, he saw both realities crumble, with his father jailed, brother targeted, and sister at risk with nobody to protect her, while the doctor he was supposed to intern for ignored him and effectively sabotaged him (though sabotage implies paying attention)
He triggered while cut off from both paths.
Broke away and just left both lives behind, throwing himself into his work. He's not so much a crime lord as a scientist of ill repute - he creates his work, studies it, and trades the research info gleaned for parahuman studies, in the hopes of figuring it all out.
He's very independent and because he threw himself into his work, he's pretty driven and single-minded about it. - Comments for WildBow
↑“-And they have thinkers. You worked the genetic material of people with powers into your giant, to give it the strength to stand despite its own weight. It’s tougher than it would appear.” - Excerpt from Eclipse x.7
↑The territory is on lock. South Boston is ours, with some office space given to some other villains. - Excerpt from Eclipse x.7
↑“Before you do, let me make you an alternate offer. You do mercenary work?”
“I’d like to hire you for a task.”
“I’d like certain items stolen from a rival. I can describe them to you and show you photographs. Do this for me, and we’ll waive the fee for entering my territory. Also, I’ll concede to have my share cut down to a mere ten percent.”
“Blasto. A tinker. Not quite the destructive personality his name implies.”
“I read up on him. Blasto from the latin prefix, meaning bud, germination or seed. Tinker botanist, grows walking, sentient plants in giant glass tubes.”
Accord gave Trickster an approving nod. “Yes. Tinkers are… bothersome. Tinkers who work wet are especially bothersome. They build, they learn from past research and past projects, each thing is created more elegantly or faster with the tools they’ve designed and amassed over time. A tinker designs a better welding torch, to use an analogy, and that allows him or her to build a better power drill. And so the cycle continues. Steal Blasto’s tools for my trophy case, it will set him back weeks or months. I’ll give you a further bonus if you destroy any other projects of his, as well as any computers or blueprints.”
“Dangerous, to attack a tinker in his lair.”
“Ah, you want more than just the waiving of your hospitality fee?”
Trickster was careful to be diplomatic. “No offense intended. If Blasto was that easy to handle, I’m sure you would have dealt with him already.”